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As a consequence of diminished drug clearance and an elevated danger of drug accumulation, patients with hepatic disorder or hepatic dysfunction must be prescribed testosterone with warning. In addition, edema secondary to drinking water and sodium retention may possibly happen through treatment method with androgens. Use testosterone with caution
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Intranasal formulations of testosterone (e.g., Natesto) usually are not advisable for individuals by using a historical past of nasal Ailments for instance nasal polyps; nasal septal perforation; nasal surgical treatment; nasal trauma leading to nasal fracture within the earlier six months or nasal fracture that triggered a deviated anterior nasal